STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDZ43973.1Fe-S type hydro-lyases tartrate/fumarate beta protein; [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain. (221 aa)    
Predicted Functional Partners:
EDZ43328.1
Hydrolyase, tartrate/fumarate subfamily, alpha subunit; [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.
 
 0.998
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.983
frdB
[C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
 
 
 0.983
RB2083_49
[C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 
  
  0.979
EDZ42158.1
Conserved hypothetical protein.
  
 
 0.968
sdhC_1
[C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
  
 
 0.962
gltA
[C] COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.933
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.922
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.902
EDZ43280.1
Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme.
  
 
 0.853
Your Current Organism:
Rhodobacteraceae bacterium HTCC2083
NCBI taxonomy Id: 314270
Other names: R. bacterium HTCC2083, Rhodobacterales bacterium HTCC2083
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