node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDZ44021.1 | cbiC | RB2083_3536 | RB2083_1237 | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | precorrin-8X methylmutase; [S] COG2138 Uncharacterized conserved protein. | 0.994 |
EDZ44021.1 | cbiD | RB2083_3536 | RB2083_372 | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.999 |
EDZ44021.1 | cobB | RB2083_3536 | RB2083_3327 | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.989 |
EDZ44021.1 | cobH | RB2083_3536 | RB2083_860 | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | precorrin-8X methylmutase; [H] COG2082 Precorrin isomerase. | 0.999 |
EDZ44021.1 | cobI | RB2083_3536 | RB2083_2002 | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | Precorrin-2 C20-methyltransferase; [H] COG1010 Precorrin-3B methylase; Belongs to the precorrin methyltransferase family. | 0.999 |
EDZ44021.1 | cobK | RB2083_3536 | RB2083_3707 | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | [H] COG2099 Precorrin-6x reductase. | 0.997 |
EDZ44021.1 | cobL | RB2083_3536 | RB2083_170 | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | precorrin-6Y C5,15-methyltransferase protein; [H] COG2241 Precorrin-6B methylase 1. | 0.999 |
EDZ44021.1 | cobM | RB2083_3536 | RB2083_3792 | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | Precorrin-4 C11-methyltransferase; [H] COG1010 Precorrin-3B methylase. | 0.999 |
EDZ44021.1 | cobQ | RB2083_3536 | RB2083_1754 | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.997 |
EDZ44021.1 | cobS_1 | RB2083_3536 | RB2083_2073 | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.986 |
cbiC | EDZ44021.1 | RB2083_1237 | RB2083_3536 | precorrin-8X methylmutase; [S] COG2138 Uncharacterized conserved protein. | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | 0.994 |
cbiC | cbiD | RB2083_1237 | RB2083_372 | precorrin-8X methylmutase; [S] COG2138 Uncharacterized conserved protein. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.861 |
cbiC | cobB | RB2083_1237 | RB2083_3327 | precorrin-8X methylmutase; [S] COG2138 Uncharacterized conserved protein. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.751 |
cbiC | cobH | RB2083_1237 | RB2083_860 | precorrin-8X methylmutase; [S] COG2138 Uncharacterized conserved protein. | precorrin-8X methylmutase; [H] COG2082 Precorrin isomerase. | 0.917 |
cbiC | cobI | RB2083_1237 | RB2083_2002 | precorrin-8X methylmutase; [S] COG2138 Uncharacterized conserved protein. | Precorrin-2 C20-methyltransferase; [H] COG1010 Precorrin-3B methylase; Belongs to the precorrin methyltransferase family. | 0.973 |
cbiC | cobK | RB2083_1237 | RB2083_3707 | precorrin-8X methylmutase; [S] COG2138 Uncharacterized conserved protein. | [H] COG2099 Precorrin-6x reductase. | 0.698 |
cbiC | cobL | RB2083_1237 | RB2083_170 | precorrin-8X methylmutase; [S] COG2138 Uncharacterized conserved protein. | precorrin-6Y C5,15-methyltransferase protein; [H] COG2241 Precorrin-6B methylase 1. | 0.975 |
cbiC | cobM | RB2083_1237 | RB2083_3792 | precorrin-8X methylmutase; [S] COG2138 Uncharacterized conserved protein. | Precorrin-4 C11-methyltransferase; [H] COG1010 Precorrin-3B methylase. | 0.744 |
cbiC | cobS_1 | RB2083_1237 | RB2083_2073 | precorrin-8X methylmutase; [S] COG2138 Uncharacterized conserved protein. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.463 |
cbiD | EDZ44021.1 | RB2083_372 | RB2083_3536 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | precorrin-3B methylase; [H] COG2073 Cobalamin biosynthesis protein CbiG. | 0.999 |