STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDZ44133.1Thioesterase family protein; [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism. (130 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.686
EDZ44261.1
[H] COG1541 Coenzyme F390 synthetase.
 
 
 0.658
EDZ41822.1
[I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
 
     0.628
EDZ42005.1
Reductive dehalogenase subfamily, putative; [C] COG1600 Uncharacterized Fe-S protein.
  
 
  0.594
EDZ42304.1
Vanillate O-demethylase oxidoreductase; [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
  
 
  0.556
paaK
Phenylacetic acid degradation oxidoreductase PaaK; [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
  
 
  0.556
RB2083_85
Vanillate O-demethylase oxidoreductase; [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
  
 
  0.556
paaH
phenylacetate-CoA oxygenase, PaaH subunit; [Q] COG3460 Uncharacterized enzyme of phenylacetate metabolism.
  
 
 0.517
EDZ44514.1
Branched-chain amino acid ABC transporter, ATP-binding protein; [R] COG1137 ABC-type (unclassified) transport system, ATPase component.
  
  
  0.486
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
       0.485
Your Current Organism:
Rhodobacteraceae bacterium HTCC2083
NCBI taxonomy Id: 314270
Other names: R. bacterium HTCC2083, Rhodobacterales bacterium HTCC2083
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