node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDZ41345.1 | EDZ41807.1 | RB2083_859 | RB2083_1322 | [R] COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases. | N-acetylmuramoyl-L-alanine amidase, family 2; [V] COG3023 Negative regulator of beta-lactamase expression. | 0.539 |
EDZ41345.1 | EDZ42203.1 | RB2083_859 | RB2083_1718 | [R] COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases. | Beta-hexosaminidase, putative; [G] COG1472 Beta-glucosidase-related glycosidases. | 0.936 |
EDZ41345.1 | anmK | RB2083_859 | RB2083_725 | [R] COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.468 |
EDZ41807.1 | EDZ41345.1 | RB2083_1322 | RB2083_859 | N-acetylmuramoyl-L-alanine amidase, family 2; [V] COG3023 Negative regulator of beta-lactamase expression. | [R] COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases. | 0.539 |
EDZ41807.1 | EDZ42203.1 | RB2083_1322 | RB2083_1718 | N-acetylmuramoyl-L-alanine amidase, family 2; [V] COG3023 Negative regulator of beta-lactamase expression. | Beta-hexosaminidase, putative; [G] COG1472 Beta-glucosidase-related glycosidases. | 0.631 |
EDZ41807.1 | anmK | RB2083_1322 | RB2083_725 | N-acetylmuramoyl-L-alanine amidase, family 2; [V] COG3023 Negative regulator of beta-lactamase expression. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.581 |
EDZ42203.1 | EDZ41345.1 | RB2083_1718 | RB2083_859 | Beta-hexosaminidase, putative; [G] COG1472 Beta-glucosidase-related glycosidases. | [R] COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases. | 0.936 |
EDZ42203.1 | EDZ41807.1 | RB2083_1718 | RB2083_1322 | Beta-hexosaminidase, putative; [G] COG1472 Beta-glucosidase-related glycosidases. | N-acetylmuramoyl-L-alanine amidase, family 2; [V] COG3023 Negative regulator of beta-lactamase expression. | 0.631 |
EDZ42203.1 | anmK | RB2083_1718 | RB2083_725 | Beta-hexosaminidase, putative; [G] COG1472 Beta-glucosidase-related glycosidases. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.742 |
EDZ43577.1 | anmK | RB2083_3092 | RB2083_725 | Hypothetical protein. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.566 |
EDZ43577.1 | tyrS | RB2083_3092 | RB2083_1698 | Hypothetical protein. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.773 |
anmK | EDZ41345.1 | RB2083_725 | RB2083_859 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | [R] COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases. | 0.468 |
anmK | EDZ41807.1 | RB2083_725 | RB2083_1322 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | N-acetylmuramoyl-L-alanine amidase, family 2; [V] COG3023 Negative regulator of beta-lactamase expression. | 0.581 |
anmK | EDZ42203.1 | RB2083_725 | RB2083_1718 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Beta-hexosaminidase, putative; [G] COG1472 Beta-glucosidase-related glycosidases. | 0.742 |
anmK | EDZ43577.1 | RB2083_725 | RB2083_3092 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Hypothetical protein. | 0.566 |
anmK | gcvP | RB2083_725 | RB2083_2790 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.406 |
anmK | mltG | RB2083_725 | RB2083_315 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.480 |
anmK | ribD | RB2083_725 | RB2083_279 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.517 |
anmK | tyrS | RB2083_725 | RB2083_1698 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.724 |
anmK | uvrC | RB2083_725 | RB2083_3525 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.431 |