STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ11806.1Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. (153 aa)    
Predicted Functional Partners:
EAQ13735.1
COG0440 Acetolactate synthase, small (regulatory) subunit.
  
 0.960
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
 
 0.838
EAQ12770.1
COG1171 Threonine dehydratase.
  
 0.781
EAQ14107.1
Phosphate acetyltransferase; COG0281 Malic enzyme.
  
 
 0.755
EAQ15065.1
COG0281 Malic enzyme.
  
 
 0.755
EAQ11793.1
4,5-dihydroxyphthalate decarboxylase; COG4521 ABC-type taurine transport system, periplasmic component.
  
     0.754
EAQ10538.1
4,5-dihydroxyphthalate decarboxylase; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.
  
     0.753
EAQ10532.1
Hypothetical protein; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold.
  
     0.725
EAQ10534.1
COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.
  
  
  0.713
EAQ11805.1
Hypothetical protein.
      0.711
Your Current Organism:
Maritimibacter alkaliphilus
NCBI taxonomy Id: 314271
Other names: M. alkaliphilus HTCC2654, Maritimibacter alkaliphilus HTCC2654, Maritimibacter alkaliphilus str. HTCC2654, Maritimibacter alkaliphilus strain HTCC2654, Rhodobacterales bacterium HTCC2654
Server load: very high (>100%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.