| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ10431.1 | EAQ10991.1 | RB2654_05510 | RB2654_18016 | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family. | Putative adenylate/guanylate cyclase transmembrane protein; COG4252 Predicted transmembrane sensor domain. | 0.892 |
| EAQ10431.1 | EAQ11457.1 | RB2654_05510 | RB2654_01810 | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family. | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | 0.627 |
| EAQ10431.1 | EAQ14889.1 | RB2654_05510 | RB2654_19938 | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family. | Putative diguanylate phosphodiesterase (EAL domain) with GAF sensor; COG2200 FOG: EAL domain. | 0.916 |
| EAQ10431.1 | ribB | RB2654_05510 | RB2654_07154 | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.811 |
| EAQ10991.1 | EAQ10431.1 | RB2654_18016 | RB2654_05510 | Putative adenylate/guanylate cyclase transmembrane protein; COG4252 Predicted transmembrane sensor domain. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family. | 0.892 |
| EAQ10991.1 | EAQ11457.1 | RB2654_18016 | RB2654_01810 | Putative adenylate/guanylate cyclase transmembrane protein; COG4252 Predicted transmembrane sensor domain. | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | 0.723 |
| EAQ10991.1 | EAQ14889.1 | RB2654_18016 | RB2654_19938 | Putative adenylate/guanylate cyclase transmembrane protein; COG4252 Predicted transmembrane sensor domain. | Putative diguanylate phosphodiesterase (EAL domain) with GAF sensor; COG2200 FOG: EAL domain. | 0.967 |
| EAQ10991.1 | ribB | RB2654_18016 | RB2654_07154 | Putative adenylate/guanylate cyclase transmembrane protein; COG4252 Predicted transmembrane sensor domain. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.892 |
| EAQ11457.1 | EAQ10431.1 | RB2654_01810 | RB2654_05510 | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family. | 0.627 |
| EAQ11457.1 | EAQ10991.1 | RB2654_01810 | RB2654_18016 | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | Putative adenylate/guanylate cyclase transmembrane protein; COG4252 Predicted transmembrane sensor domain. | 0.723 |
| EAQ11457.1 | EAQ13640.1 | RB2654_01810 | RB2654_02964 | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | Hypothetical protein; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases. | 0.972 |
| EAQ11457.1 | EAQ14040.1 | RB2654_01810 | RB2654_13244 | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | COG3222 Uncharacterized protein conserved in bacteria. | 0.800 |
| EAQ11457.1 | EAQ14828.1 | RB2654_01810 | RB2654_19633 | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | Glycosyl transferase, group 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis. | 0.788 |
| EAQ11457.1 | EAQ14889.1 | RB2654_01810 | RB2654_19938 | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | Putative diguanylate phosphodiesterase (EAL domain) with GAF sensor; COG2200 FOG: EAL domain. | 0.548 |
| EAQ11457.1 | hemE | RB2654_01810 | RB2654_10069 | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.867 |
| EAQ11457.1 | pgl | RB2654_01810 | RB2654_01820 | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 0.583 |
| EAQ11457.1 | ribB | RB2654_01810 | RB2654_07154 | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.627 |
| EAQ11457.1 | zwf | RB2654_01810 | RB2654_01815 | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.582 |
| EAQ13640.1 | EAQ11457.1 | RB2654_02964 | RB2654_01810 | Hypothetical protein; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases. | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. | 0.972 |
| EAQ13640.1 | EAQ14040.1 | RB2654_02964 | RB2654_13244 | Hypothetical protein; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases. | COG3222 Uncharacterized protein conserved in bacteria. | 0.653 |