| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ10431.1 | EAQ12599.1 | RB2654_05510 | RB2654_14975 | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family. | COG0167 Dihydroorotate dehydrogenase. | 0.551 |
| EAQ10431.1 | ribB | RB2654_05510 | RB2654_07154 | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.811 |
| EAQ10431.1 | tadA | RB2654_05510 | RB2654_08562 | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family. | Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.851 |
| EAQ11608.1 | EAQ12599.1 | RB2654_04234 | RB2654_14975 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | COG0167 Dihydroorotate dehydrogenase. | 0.468 |
| EAQ11608.1 | EAQ12703.1 | RB2654_04234 | RB2654_06324 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Hypothetical protein; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | 0.440 |
| EAQ11608.1 | EAQ13675.1 | RB2654_04234 | RB2654_03139 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | COG1957 Inosine-uridine nucleoside N-ribohydrolase. | 0.902 |
| EAQ11608.1 | tadA | RB2654_04234 | RB2654_08562 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.843 |
| EAQ11608.1 | upp | RB2654_04234 | RB2654_20838 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.475 |
| EAQ12599.1 | EAQ10431.1 | RB2654_14975 | RB2654_05510 | COG0167 Dihydroorotate dehydrogenase. | Bifunctional GTP cyclohydrolaseII/3,4-dihydroxy-2butanone-4-phosphate synthase; COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family. | 0.551 |
| EAQ12599.1 | EAQ11608.1 | RB2654_14975 | RB2654_04234 | COG0167 Dihydroorotate dehydrogenase. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.468 |
| EAQ12599.1 | EAQ12703.1 | RB2654_14975 | RB2654_06324 | COG0167 Dihydroorotate dehydrogenase. | Hypothetical protein; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | 0.854 |
| EAQ12599.1 | EAQ13675.1 | RB2654_14975 | RB2654_03139 | COG0167 Dihydroorotate dehydrogenase. | COG1957 Inosine-uridine nucleoside N-ribohydrolase. | 0.451 |
| EAQ12599.1 | ribB | RB2654_14975 | RB2654_07154 | COG0167 Dihydroorotate dehydrogenase. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.551 |
| EAQ12599.1 | tadA | RB2654_14975 | RB2654_08562 | COG0167 Dihydroorotate dehydrogenase. | Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.789 |
| EAQ12599.1 | upp | RB2654_14975 | RB2654_20838 | COG0167 Dihydroorotate dehydrogenase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.941 |
| EAQ12703.1 | EAQ11608.1 | RB2654_06324 | RB2654_04234 | Hypothetical protein; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.440 |
| EAQ12703.1 | EAQ12599.1 | RB2654_06324 | RB2654_14975 | Hypothetical protein; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG0167 Dihydroorotate dehydrogenase. | 0.854 |
| EAQ12703.1 | EAQ13675.1 | RB2654_06324 | RB2654_03139 | Hypothetical protein; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG1957 Inosine-uridine nucleoside N-ribohydrolase. | 0.715 |
| EAQ12703.1 | EAQ14673.1 | RB2654_06324 | RB2654_18858 | Hypothetical protein; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B. | 0.506 |
| EAQ12703.1 | EAQ14674.1 | RB2654_06324 | RB2654_18863 | Hypothetical protein; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A. | 0.481 |