| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ10760.1 | EAQ13824.1 | RB2654_05547 | RB2654_12164 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.798 |
| EAQ10760.1 | EAQ14954.1 | RB2654_05547 | RB2654_20263 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. | 0.575 |
| EAQ10760.1 | nadD | RB2654_05547 | RB2654_06077 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.742 |
| EAQ10760.1 | rlmH | RB2654_05547 | RB2654_12594 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.554 |
| EAQ13824.1 | EAQ10760.1 | RB2654_12164 | RB2654_05547 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.798 |
| EAQ13824.1 | EAQ14954.1 | RB2654_12164 | RB2654_20263 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. | 0.665 |
| EAQ13824.1 | prmA | RB2654_12164 | RB2654_08102 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal protein L11 methyltransferase, putative; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.722 |
| EAQ13824.1 | rlmH | RB2654_12164 | RB2654_12594 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.548 |
| EAQ13824.1 | rnr | RB2654_12164 | RB2654_13239 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.501 |
| EAQ13824.1 | rsfS | RB2654_12164 | RB2654_12599 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.686 |
| EAQ13824.1 | rsmI | RB2654_12164 | RB2654_08937 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.468 |
| EAQ13912.1 | rlmH | RB2654_12604 | RB2654_12594 | Mechanosensitive ion channel family protein; COG3264 Small-conductance mechanosensitive channel. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.545 |
| EAQ13912.1 | rsfS | RB2654_12604 | RB2654_12599 | Mechanosensitive ion channel family protein; COG3264 Small-conductance mechanosensitive channel. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.526 |
| EAQ14954.1 | EAQ10760.1 | RB2654_20263 | RB2654_05547 | COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.575 |
| EAQ14954.1 | EAQ13824.1 | RB2654_20263 | RB2654_12164 | COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.665 |
| EAQ14954.1 | rlmH | RB2654_20263 | RB2654_12594 | COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.539 |
| engB | prmA | RB2654_10923 | RB2654_08102 | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Ribosomal protein L11 methyltransferase, putative; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.492 |
| engB | rlmH | RB2654_10923 | RB2654_12594 | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.677 |
| engB | rnr | RB2654_10923 | RB2654_13239 | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.418 |
| engB | rsfS | RB2654_10923 | RB2654_12599 | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.926 |