STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ14107.1Phosphate acetyltransferase; COG0281 Malic enzyme. (752 aa)    
Predicted Functional Partners:
EAQ11058.1
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.992
EAQ11891.1
Fatty acid synthase transmembrane protein; COG3321 Polyketide synthase modules and related proteins.
  
 0.978
EAQ13549.1
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
    
 0.952
EAQ14153.1
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
    
 0.952
glcB
Malate synthase G protein; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.948
EAQ13210.1
Acetyltransferase, GNAT family protein; COG1042 Acyl-CoA synthetase (NDP forming).
    
 0.943
EAQ14323.1
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.936
EAQ11309.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 0.934
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.933
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.932
Your Current Organism:
Maritimibacter alkaliphilus
NCBI taxonomy Id: 314271
Other names: M. alkaliphilus HTCC2654, Maritimibacter alkaliphilus HTCC2654, Maritimibacter alkaliphilus str. HTCC2654, Maritimibacter alkaliphilus strain HTCC2654, Rhodobacterales bacterium HTCC2654
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.