| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ10664.1 | EAQ13204.1 | RB2654_06137 | RB2654_09049 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | methylmalonyl-CoA mutase-like protein; COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.877 |
| EAQ10664.1 | EAQ14107.1 | RB2654_06137 | RB2654_13579 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.898 |
| EAQ10664.1 | EAQ14332.1 | RB2654_06137 | RB2654_16721 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. | 0.750 |
| EAQ10664.1 | EAQ15065.1 | RB2654_06137 | RB2654_20818 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG0281 Malic enzyme. | 0.898 |
| EAQ10664.1 | glcB | RB2654_06137 | RB2654_01055 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate synthase G protein; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.922 |
| EAQ10664.1 | mdh | RB2654_06137 | RB2654_17316 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.935 |
| EAQ10664.1 | sucC | RB2654_06137 | RB2654_17336 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.915 |
| EAQ10664.1 | sucD | RB2654_06137 | RB2654_17346 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.911 |
| EAQ13117.1 | EAQ14332.1 | RB2654_11483 | RB2654_16721 | Hypothetical protein. | COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. | 0.786 |
| EAQ13117.1 | sucC | RB2654_11483 | RB2654_17336 | Hypothetical protein. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.543 |
| EAQ13117.1 | sucD | RB2654_11483 | RB2654_17346 | Hypothetical protein. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.538 |
| EAQ13204.1 | EAQ10664.1 | RB2654_09049 | RB2654_06137 | methylmalonyl-CoA mutase-like protein; COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.877 |
| EAQ13204.1 | EAQ14107.1 | RB2654_09049 | RB2654_13579 | methylmalonyl-CoA mutase-like protein; COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.612 |
| EAQ13204.1 | EAQ14332.1 | RB2654_09049 | RB2654_16721 | methylmalonyl-CoA mutase-like protein; COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. | 0.752 |
| EAQ13204.1 | EAQ14445.1 | RB2654_09049 | RB2654_17286 | methylmalonyl-CoA mutase-like protein; COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Hypothetical protein; COG2030 Acyl dehydratase. | 0.868 |
| EAQ13204.1 | EAQ15065.1 | RB2654_09049 | RB2654_20818 | methylmalonyl-CoA mutase-like protein; COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG0281 Malic enzyme. | 0.612 |
| EAQ13204.1 | mdh | RB2654_09049 | RB2654_17316 | methylmalonyl-CoA mutase-like protein; COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.859 |
| EAQ13204.1 | sucC | RB2654_09049 | RB2654_17336 | methylmalonyl-CoA mutase-like protein; COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.869 |
| EAQ13204.1 | sucD | RB2654_09049 | RB2654_17346 | methylmalonyl-CoA mutase-like protein; COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.879 |
| EAQ14107.1 | EAQ10664.1 | RB2654_13579 | RB2654_06137 | Phosphate acetyltransferase; COG0281 Malic enzyme. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.898 |