STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fur-2COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family. (140 aa)    
Predicted Functional Partners:
EAQ12670.1
Glutamate synthase, large subunit; COG0070 Glutamate synthase domain 3.
    
 0.916
EAQ12339.1
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 
 0.744
secA
Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
    
 0.723
EAQ14811.1
ABC Mn+2/Fe+2 transporter, ATPase subunit SitB; COG1121 ABC-type Mn/Zn transport systems, ATPase component.
 
  
 0.704
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.682
EAQ14810.1
ABC Mn+2/Fe+2 transporter, periplasmic substrate-binding protein SitA; COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.
 
  
 0.672
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   0.670
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   0.628
EAQ14217.1
Thiol-specific antioxidant protein; COG0450 Peroxiredoxin.
  
  
 0.617
EAQ10579.1
COG5394 Uncharacterized protein conserved in bacteria.
      
 0.608
Your Current Organism:
Maritimibacter alkaliphilus
NCBI taxonomy Id: 314271
Other names: M. alkaliphilus HTCC2654, Maritimibacter alkaliphilus HTCC2654, Maritimibacter alkaliphilus str. HTCC2654, Maritimibacter alkaliphilus strain HTCC2654, Rhodobacterales bacterium HTCC2654
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