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glyA protein (Maritimibacter alkaliphilus) - STRING interaction network
"glyA" - Serine hydroxymethyltransferase in Maritimibacter alkaliphilus
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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glyASerine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (430 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase (aminomethyl-transferring) ; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (953 aa)
   
 
  0.999
RB2654_18583
Aminomethyltransferase ; The glycine cleavage system catalyzes the degradation of glycine (364 aa)
 
  0.992
RB2654_16106
Phosphoserine phosphatase (292 aa)
   
  0.991
RB2654_19638
Serine--glyoxylate transaminase, putative (397 aa)
   
 
  0.987
purH
Bifunctional purine biosynthesis protein PurH (529 aa)
   
  0.983
RB2654_02144
Sarcosine oxidase, alpha subunit family protein (1004 aa)
   
  0.982
folD
Bifunctional protein FolD ; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (298 aa)
 
  0.980
RB2654_08672
Aminomethyl transferase family protein (833 aa)
   
  0.976
gcvH
Glycine cleavage system H protein ; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (119 aa)
   
 
  0.955
RB2654_11523
FolC bifunctional protein (423 aa)
   
  0.950
Your Current Organism:
Maritimibacter alkaliphilus
NCBI taxonomy Id: 314271
Other names: M. alkaliphilus, M. alkaliphilus HTCC2654, Maritimibacter, Maritimibacter Lee et al. 2007, Maritimibacter alkaliphilus, Maritimibacter alkaliphilus HTCC2654, Maritimibacter alkaliphilus Lee et al. 2007, Maritimibacter alkaliphilus str. HTCC2654, Maritimibacter alkaliphilus strain HTCC2654, Rhodobacterales bacterium HTCC2654
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