Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hdaCOG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. HdA subfamily. (242 aa)    
Predicted Functional Partners:
EAQ33361.1
DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]
  
 
 0.981
EAQ32521.1
COG3249 Uncharacterized protein conserved in bacteria.
 
     0.860
EAQ30799.1
COG0305 Replicative DNA helicase.
   
 
 0.766
EAQ33338.1
DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
 
   
 0.604
EAQ32431.1
Bacterial nucleoid DNA-binding protein, IHF alpha subunit; COG0776 Bacterial nucleoid DNA-binding protein.
   
 
 0.594
EAQ33360.1
COG1195 Recombinational DNA repair ATPase (RecF pathway).
 
  
 0.528
EAQ31386.1
COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain.
      
 0.521
EAQ32522.1
COG0477 Permeases of the major facilitator superfamily.
       0.505
EAQ32194.1
Factor for inversion stimulation Fis, transcriptional activator; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.
  
   
 0.492
ihfB
Bacterial nucleoid DNA-binding protein, IHF beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
    
 
 0.474
Your Current Organism:
Idiomarina baltica
NCBI taxonomy Id: 314276
Other names: I. baltica OS145, Idiomarina baltica OS145, Idiomarina baltica str. OS145, Idiomarina baltica strain OS145
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