| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ31041.1 | EAQ31386.1 | OS145_12146 | OS145_04675 | Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | 0.999 |
| EAQ31041.1 | EAQ32197.1 | OS145_12146 | OS145_08197 | Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. | COG0151 Phosphoribosylamine-glycine ligase. | 0.999 |
| EAQ31041.1 | EAQ33326.1 | OS145_12146 | OS145_03120 | Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. | COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase). | 0.997 |
| EAQ31041.1 | folD | OS145_12146 | OS145_12206 | Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. | 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.564 |
| EAQ31041.1 | purA | OS145_12146 | OS145_01955 | Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.827 |
| EAQ31041.1 | purC | OS145_12146 | OS145_00870 | Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.985 |
| EAQ31041.1 | purE | OS145_12146 | OS145_03125 | Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.993 |
| EAQ31041.1 | purH | OS145_12146 | OS145_08187 | Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. | COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.999 |
| EAQ31041.1 | purM | OS145_12146 | OS145_01797 | Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. | COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.998 |
| EAQ31041.1 | purN | OS145_12146 | OS145_01802 | Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. | Folate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.989 |
| EAQ31386.1 | EAQ31041.1 | OS145_04675 | OS145_12146 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. | 0.999 |
| EAQ31386.1 | EAQ32197.1 | OS145_04675 | OS145_08197 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | COG0151 Phosphoribosylamine-glycine ligase. | 0.999 |
| EAQ31386.1 | EAQ33326.1 | OS145_04675 | OS145_03120 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase). | 0.997 |
| EAQ31386.1 | folD | OS145_04675 | OS145_12206 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.904 |
| EAQ31386.1 | purA | OS145_04675 | OS145_01955 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.968 |
| EAQ31386.1 | purC | OS145_04675 | OS145_00870 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.999 |
| EAQ31386.1 | purE | OS145_04675 | OS145_03125 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
| EAQ31386.1 | purH | OS145_04675 | OS145_08187 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.998 |
| EAQ31386.1 | purM | OS145_04675 | OS145_01797 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.999 |
| EAQ31386.1 | purN | OS145_04675 | OS145_01802 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | Folate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |