STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tsaDProbable O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (339 aa)    
Predicted Functional Partners:
tsaB
COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.
  
 
 0.934
EAQ33101.1
COG0802 Predicted ATPase or kinase.
  
 
 0.894
pheT
phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain.
 
   
 0.731
EAQ33342.1
Possible translation factor, Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
 
 0.707
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; COG0518 GMP synthase - Glutamine amidotransferase domain.
     
 0.648
EAQ31668.1
Possible translation factor, Sua5/YciO/YrdC/YwlC family protein; COG0009 Putative translation factor (SUA5); Belongs to the SUA5 family.
  
 0.648
EAQ32020.1
COG0143 Methionyl-tRNA synthetase.
 
   
 0.644
lolD
ABC-type transport system, involved in lipoprotein release, ATPase component; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
 
     0.610
ksgA
COG0030 Dimethyladenosine transferase (rRNA methylation); Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
 
  
 0.602
topA
COG0550 Topoisomerase IA; Belongs to the type IA topoisomerase family.
     
 0.582
Your Current Organism:
Idiomarina baltica
NCBI taxonomy Id: 314276
Other names: I. baltica OS145, Idiomarina baltica OS145, Idiomarina baltica str. OS145, Idiomarina baltica strain OS145
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.