Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa)    
Predicted Functional Partners:
EAQ30865.1
Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 0.971
proB
Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.881
EAQ31268.1
Predicted enzyme with a TIM-barrel fold; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
 
  
 0.878
EAQ31270.1
COG0762 Predicted integral membrane protein.
  
    0.876
EAQ31280.1
COG0014 Gamma-glutamyl phosphate reductase.
 
 
 0.861
EAQ31271.1
Uncharacterized conserved secreted protein.
       0.825
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
  
 0.728
EAQ32622.1
COG0527 Aspartokinases.
 
  
 0.706
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; COG0518 GMP synthase - Glutamine amidotransferase domain.
 
  
 0.705
EAQ31267.1
PilT; COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT.
       0.668
Your Current Organism:
Idiomarina baltica
NCBI taxonomy Id: 314276
Other names: I. baltica OS145, Idiomarina baltica OS145, Idiomarina baltica str. OS145, Idiomarina baltica strain OS145
Server load: low (18%) [HD]