Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAQ31277.1A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. (345 aa)    
Predicted Functional Partners:
EAQ32369.1
SfsA; COG1489 DNA-binding protein, stimulates sugar fermentation.
 
    0.924
EAQ32502.1
COG0708 Exonuclease III.
  
 
 0.902
EAQ33361.1
DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]
    
 
 0.888
EAQ31278.1
Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
  
    0.839
mutT
7,8-dihydro-8-oxoguanine-triphosphatase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
  
 
 0.602
EAQ33338.1
DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
   
  
 0.600
mutL
DNA mismatch repair enzyme, ATPase; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.599
trpC
Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
  
  
 0.594
EAQ31280.1
COG0014 Gamma-glutamyl phosphate reductase.
  
  
 0.575
proB
Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
     
 0.570
Your Current Organism:
Idiomarina baltica
NCBI taxonomy Id: 314276
Other names: I. baltica OS145, Idiomarina baltica OS145, Idiomarina baltica str. OS145, Idiomarina baltica strain OS145
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