| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ31453.1 | dxr | OS145_10085 | OS145_13124 | COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.409 |
| EAQ31453.1 | dxs | OS145_10085 | OS145_04413 | COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.670 |
| EAQ31854.1 | EAQ32060.1 | OS145_11127 | OS145_07282 | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; COG0761 Penicillin tolerance protein. | COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | 0.887 |
| EAQ31854.1 | EAQ32061.1 | OS145_11127 | OS145_07287 | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; COG0761 Penicillin tolerance protein. | COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase. | 0.881 |
| EAQ31854.1 | EAQ33042.1 | OS145_11127 | OS145_04408 | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; COG0761 Penicillin tolerance protein. | COG0142 Geranylgeranyl pyrophosphate synthase. | 0.937 |
| EAQ31854.1 | dxr | OS145_11127 | OS145_13124 | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; COG0761 Penicillin tolerance protein. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.890 |
| EAQ31854.1 | dxs | OS145_11127 | OS145_04413 | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; COG0761 Penicillin tolerance protein. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.855 |
| EAQ31854.1 | ispE | OS145_11127 | OS145_12619 | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; COG0761 Penicillin tolerance protein. | 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.787 |
| EAQ31854.1 | ispG | OS145_11127 | OS145_04855 | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; COG0761 Penicillin tolerance protein. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.994 |
| EAQ32060.1 | EAQ31854.1 | OS145_07282 | OS145_11127 | COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; COG0761 Penicillin tolerance protein. | 0.887 |
| EAQ32060.1 | EAQ32061.1 | OS145_07282 | OS145_07287 | COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase. | 0.999 |
| EAQ32060.1 | EAQ33042.1 | OS145_07282 | OS145_04408 | COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | COG0142 Geranylgeranyl pyrophosphate synthase. | 0.451 |
| EAQ32060.1 | dxr | OS145_07282 | OS145_13124 | COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.939 |
| EAQ32060.1 | dxs | OS145_07282 | OS145_04413 | COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.870 |
| EAQ32060.1 | ispE | OS145_07282 | OS145_12619 | COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.980 |
| EAQ32060.1 | ispG | OS145_07282 | OS145_04855 | COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.994 |
| EAQ32061.1 | EAQ31854.1 | OS145_07287 | OS145_11127 | COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase. | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; COG0761 Penicillin tolerance protein. | 0.881 |
| EAQ32061.1 | EAQ32060.1 | OS145_07287 | OS145_07282 | COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase. | COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | 0.999 |
| EAQ32061.1 | EAQ33042.1 | OS145_07287 | OS145_04408 | COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase. | COG0142 Geranylgeranyl pyrophosphate synthase. | 0.471 |
| EAQ32061.1 | dxr | OS145_07287 | OS145_13124 | COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.994 |