Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (371 aa)    
Predicted Functional Partners:
EAQ32060.1
COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
 
  
 0.994
EAQ31854.1
4-Hydroxy-3-methylbut-2-enyl diphosphate reductase; COG0761 Penicillin tolerance protein.
 
  
 0.994
EAQ32061.1
COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase.
 
  
 0.927
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
 
  
 0.894
EAQ31423.1
Predicted transcriptional regulator, contains N-terminal xre-type HTH domain; COG1426 Uncharacterized protein conserved in bacteria.
  
    0.888
EAQ31421.1
COG0124 Histidyl-tRNA synthetase.
  
  
 0.870
dxs
Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
 
   
 0.819
EAQ31420.1
COG2976 Uncharacterized protein conserved in bacteria.
  
    0.698
ispE
4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
  
  
 0.693
EAQ31418.1
GTP-binding protein EngA; COG1160 Predicted GTPases; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
      0.684
Your Current Organism:
Idiomarina baltica
NCBI taxonomy Id: 314276
Other names: I. baltica OS145, Idiomarina baltica OS145, Idiomarina baltica str. OS145, Idiomarina baltica strain OS145
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