| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ31081.1 | EAQ31428.1 | OS145_11981 | OS145_04885 | NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | 0.935 |
| EAQ31081.1 | EAQ32115.1 | OS145_11981 | OS145_12829 | NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | COG0633 Ferredoxin. | 0.684 |
| EAQ31081.1 | EAQ33251.1 | OS145_11981 | OS145_02745 | NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Fe-S cluster assembly scaffold protein. | 0.579 |
| EAQ31081.1 | djlA | OS145_11981 | OS145_07856 | NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Dna-J like membrane chaperone protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.713 |
| EAQ31081.1 | dnaK | OS145_11981 | OS145_12320 | NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | COG0443 Molecular chaperone. | 0.852 |
| EAQ31081.1 | erpA | OS145_11981 | OS145_07926 | NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | HesB/IscA family protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.569 |
| EAQ31081.1 | iscR | OS145_11981 | OS145_04890 | NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Predicted transcriptional regulator, YjeB/RRF2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.776 |
| EAQ31081.1 | nfuA | OS145_11981 | OS145_02245 | NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.972 |
| EAQ31081.1 | thiI | OS145_11981 | OS145_04388 | NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.996 |
| EAQ31081.1 | tusA | OS145_11981 | OS145_03260 | NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Predicted redox protein, regulator of disulfide bond formation; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.994 |
| EAQ31428.1 | EAQ31081.1 | OS145_04885 | OS145_11981 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | 0.935 |
| EAQ31428.1 | EAQ32115.1 | OS145_04885 | OS145_12829 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | COG0633 Ferredoxin. | 0.815 |
| EAQ31428.1 | EAQ33251.1 | OS145_04885 | OS145_02745 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Fe-S cluster assembly scaffold protein. | 0.883 |
| EAQ31428.1 | djlA | OS145_04885 | OS145_07856 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Dna-J like membrane chaperone protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.646 |
| EAQ31428.1 | dnaK | OS145_04885 | OS145_12320 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | COG0443 Molecular chaperone. | 0.775 |
| EAQ31428.1 | erpA | OS145_04885 | OS145_07926 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | HesB/IscA family protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.702 |
| EAQ31428.1 | iscR | OS145_04885 | OS145_04890 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Predicted transcriptional regulator, YjeB/RRF2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.980 |
| EAQ31428.1 | nfuA | OS145_04885 | OS145_02245 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.929 |
| EAQ31428.1 | thiI | OS145_04885 | OS145_04388 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.970 |
| EAQ31428.1 | tusA | OS145_04885 | OS145_03260 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Predicted redox protein, regulator of disulfide bond formation; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.989 |