| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ30810.1 | EAQ30958.1 | OS145_03542 | OS145_12101 | Biotin operon repressor/biotin--protein ligase fusion protein; COG1654 Biotin operon repressor. | COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.650 |
| EAQ30810.1 | EAQ31218.1 | OS145_03542 | OS145_05997 | Biotin operon repressor/biotin--protein ligase fusion protein; COG1654 Biotin operon repressor. | COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.869 |
| EAQ30810.1 | EAQ31219.1 | OS145_03542 | OS145_06002 | Biotin operon repressor/biotin--protein ligase fusion protein; COG1654 Biotin operon repressor. | Biotin synthesis protein; COG0500 SAM-dependent methyltransferases. | 0.474 |
| EAQ30810.1 | EAQ31220.1 | OS145_03542 | OS145_06007 | Biotin operon repressor/biotin--protein ligase fusion protein; COG1654 Biotin operon repressor. | COG0132 Dethiobiotin synthetase. | 0.663 |
| EAQ30810.1 | EAQ33002.1 | OS145_03542 | OS145_04208 | Biotin operon repressor/biotin--protein ligase fusion protein; COG1654 Biotin operon repressor. | COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain. | 0.424 |
| EAQ30810.1 | bioA | OS145_03542 | OS145_05987 | Biotin operon repressor/biotin--protein ligase fusion protein; COG1654 Biotin operon repressor. | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.606 |
| EAQ30810.1 | bioB | OS145_03542 | OS145_05992 | Biotin operon repressor/biotin--protein ligase fusion protein; COG1654 Biotin operon repressor. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.928 |
| EAQ30810.1 | kbl | OS145_03542 | OS145_02130 | Biotin operon repressor/biotin--protein ligase fusion protein; COG1654 Biotin operon repressor. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.869 |
| EAQ30958.1 | EAQ30810.1 | OS145_12101 | OS145_03542 | COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Biotin operon repressor/biotin--protein ligase fusion protein; COG1654 Biotin operon repressor. | 0.650 |
| EAQ30958.1 | EAQ31219.1 | OS145_12101 | OS145_06002 | COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Biotin synthesis protein; COG0500 SAM-dependent methyltransferases. | 0.807 |
| EAQ30958.1 | EAQ31220.1 | OS145_12101 | OS145_06007 | COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | COG0132 Dethiobiotin synthetase. | 0.616 |
| EAQ31218.1 | EAQ30810.1 | OS145_05997 | OS145_03542 | COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | Biotin operon repressor/biotin--protein ligase fusion protein; COG1654 Biotin operon repressor. | 0.869 |
| EAQ31218.1 | EAQ31219.1 | OS145_05997 | OS145_06002 | COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | Biotin synthesis protein; COG0500 SAM-dependent methyltransferases. | 0.959 |
| EAQ31218.1 | EAQ31220.1 | OS145_05997 | OS145_06007 | COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | COG0132 Dethiobiotin synthetase. | 0.983 |
| EAQ31218.1 | EAQ33002.1 | OS145_05997 | OS145_04208 | COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain. | 0.900 |
| EAQ31218.1 | bioA | OS145_05997 | OS145_05987 | COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.983 |
| EAQ31218.1 | bioB | OS145_05997 | OS145_05992 | COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.974 |
| EAQ31218.1 | bioH | OS145_05997 | OS145_02255 | COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | Alpha/beta superfamily hydrolase; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.908 |
| EAQ31219.1 | EAQ30810.1 | OS145_06002 | OS145_03542 | Biotin synthesis protein; COG0500 SAM-dependent methyltransferases. | Biotin operon repressor/biotin--protein ligase fusion protein; COG1654 Biotin operon repressor. | 0.474 |
| EAQ31219.1 | EAQ30958.1 | OS145_06002 | OS145_12101 | Biotin synthesis protein; COG0500 SAM-dependent methyltransferases. | COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.807 |