STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ31222.1Heat shock protein HtpX; COG0501 Zn-dependent protease with chaperone function. (291 aa)    
Predicted Functional Partners:
hflB
COG0465 ATP-dependent Zn proteases.
   
 0.860
grpE
Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]
  
  
 0.711
EAQ31200.1
COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain.
  
 
 0.700
hslU
ATP-dependent protease ATP-binding subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
   
  
 0.663
EAQ30998.1
COG0201 Preprotein translocase subunit SecY.
  
 
 0.658
dnaK
COG0443 Molecular chaperone.
  
 
 0.635
EAQ31788.1
COG0670 Integral membrane protein, interacts with FtsH; Belongs to the BI1 family.
  
  
 0.633
EAQ31223.1
COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase.
       0.596
EAQ31453.1
COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase.
     
 0.581
EAQ31033.1
COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.579
Your Current Organism:
Idiomarina baltica
NCBI taxonomy Id: 314276
Other names: I. baltica OS145, Idiomarina baltica OS145, Idiomarina baltica str. OS145, Idiomarina baltica strain OS145
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.