Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
msrBCOG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family. (137 aa)    
Predicted Functional Partners:
EAQ31427.1
COG0225 Peptide methionine sulfoxide reductase.
 
 0.993
EAQ31314.1
COG3139 Uncharacterized protein conserved in bacteria.
  
    0.959
EAQ32090.1
Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
      0.730
grpE
Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]
 
 
 
 0.580
EAQ31337.1
Thiol:disulfide interchange protein; COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis.
   
 
 0.575
pyk
Pyruvate kinase II, glucose stimulated; COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
       0.571
dsbD
COG4232 Thiol:disulfide interchange protein.
    
 
 0.553
EAQ32211.1
COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.
 
      0.546
sdhD
COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.
   
    0.528
sdhC
COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
   
    0.524
Your Current Organism:
Idiomarina baltica
NCBI taxonomy Id: 314276
Other names: I. baltica OS145, Idiomarina baltica OS145, Idiomarina baltica str. OS145, Idiomarina baltica strain OS145
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