Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
mutSCOG0249 Mismatch repair ATPase (MutS family); Belongs to the DNA mismatch repair MutS family. (853 aa)    
Predicted Functional Partners:
mutL
DNA mismatch repair enzyme, ATPase; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
 0.996
EAQ33338.1
DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
   
 0.935
EAQ33361.1
DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]
  
 0.929
recA
COG0468 RecA/RadA recombinase.
   
 0.890
recQ
COG0514 Superfamily II DNA helicase.
  
 0.837
topA
COG0550 Topoisomerase IA; Belongs to the type IA topoisomerase family.
   
 0.757
EAQ32052.1
COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.
  
  
 0.693
EAQ31757.1
COG2003 DNA repair proteins.
 
   
 0.597
recJ
RecJ; COG0608 Single-stranded DNA-specific exonuclease.
  
  
 0.576
EAQ31368.1
COG0629 Single-stranded DNA-binding protein.
    
 
 0.560
Your Current Organism:
Idiomarina baltica
NCBI taxonomy Id: 314276
Other names: I. baltica OS145, Idiomarina baltica OS145, Idiomarina baltica str. OS145, Idiomarina baltica strain OS145
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