| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ31328.1 | EAQ31453.1 | OS145_06342 | OS145_10085 | Hypothetical protein; COG0720 6-pyruvoyl-tetrahydropterin synthase. | COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase. | 0.406 |
| EAQ31328.1 | EAQ32090.1 | OS145_06342 | OS145_12704 | Hypothetical protein; COG0720 6-pyruvoyl-tetrahydropterin synthase. | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.960 |
| EAQ31328.1 | queE | OS145_06342 | OS145_12709 | Hypothetical protein; COG0720 6-pyruvoyl-tetrahydropterin synthase. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.954 |
| EAQ31328.1 | queF | OS145_06342 | OS145_13034 | Hypothetical protein; COG0720 6-pyruvoyl-tetrahydropterin synthase. | GTP cyclohydrolase I related protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.926 |
| EAQ31453.1 | EAQ31328.1 | OS145_10085 | OS145_06342 | COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase. | Hypothetical protein; COG0720 6-pyruvoyl-tetrahydropterin synthase. | 0.406 |
| EAQ31453.1 | EAQ32090.1 | OS145_10085 | OS145_12704 | COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase. | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.549 |
| EAQ31453.1 | guaA | OS145_10085 | OS145_04735 | COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase. | Bifunctional GMP synthase/glutamine amidotransferase protein; COG0518 GMP synthase - Glutamine amidotransferase domain. | 0.740 |
| EAQ31453.1 | queF | OS145_10085 | OS145_13034 | COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase. | GTP cyclohydrolase I related protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.728 |
| EAQ31453.1 | ribD | OS145_10085 | OS145_10080 | COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase. | Riboflavin-specific deaminase/reductase; COG0117 Pyrimidine deaminase. | 0.999 |
| EAQ32090.1 | EAQ31328.1 | OS145_12704 | OS145_06342 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Hypothetical protein; COG0720 6-pyruvoyl-tetrahydropterin synthase. | 0.960 |
| EAQ32090.1 | EAQ31453.1 | OS145_12704 | OS145_10085 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase. | 0.549 |
| EAQ32090.1 | guaA | OS145_12704 | OS145_04735 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Bifunctional GMP synthase/glutamine amidotransferase protein; COG0518 GMP synthase - Glutamine amidotransferase domain. | 0.563 |
| EAQ32090.1 | msrB | OS145_12704 | OS145_06302 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | 0.730 |
| EAQ32090.1 | queA | OS145_12704 | OS145_07746 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | S-adenosylmethionine:tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.610 |
| EAQ32090.1 | queE | OS145_12704 | OS145_12709 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
| EAQ32090.1 | queF | OS145_12704 | OS145_13034 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | GTP cyclohydrolase I related protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.988 |
| EAQ32090.1 | queG | OS145_12704 | OS145_02005 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative 4Fe-4S binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.556 |
| EAQ32090.1 | ribD | OS145_12704 | OS145_10080 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Riboflavin-specific deaminase/reductase; COG0117 Pyrimidine deaminase. | 0.549 |
| EAQ32090.1 | tgt | OS145_12704 | OS145_07741 | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | tRNA-guanine transglycosylase; COG0343 Queuine/archaeosine tRNA-ribosyltransferase. | 0.566 |
| guaA | EAQ31453.1 | OS145_04735 | OS145_10085 | Bifunctional GMP synthase/glutamine amidotransferase protein; COG0518 GMP synthase - Glutamine amidotransferase domain. | COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase. | 0.740 |