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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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gene co-occurrence
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[Homology]
Score
gptXanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (161 aa)    
Predicted Functional Partners:
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; COG0518 GMP synthase - Glutamine amidotransferase domain.
  
 0.945
EAQ32116.1
Hypothetical protein; COG2252 Permeases.
  
  
 0.847
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.818
EAQ31399.1
COG0516 IMP dehydrogenase/GMP reductase.
  
 
 0.780
EAQ31386.1
COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain.
  
  
 0.772
EAQ31230.1
COG0015 Adenylosuccinate lyase.
  
 0.754
rdgB
Xanthosine triphosphate pyrophosphatase related enzyme; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
 0.748
surE
SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.732
purH
COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).
  
 0.706
EAQ32857.1
COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.
    
 0.705
Your Current Organism:
Idiomarina baltica
NCBI taxonomy Id: 314276
Other names: I. baltica OS145, Idiomarina baltica OS145, Idiomarina baltica str. OS145, Idiomarina baltica strain OS145
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