| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ63338.1 | EAQ63595.1 | MED121_03130 | MED121_00265 | Hypothetical protein; COG0637 Predicted phosphatase/phosphohexomutase. | Alpha-glucosidase; COG0366 Glycosidases. | 0.407 |
| EAQ63338.1 | EAQ63596.1 | MED121_03130 | MED121_00270 | Hypothetical protein; COG0637 Predicted phosphatase/phosphohexomutase. | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | 0.686 |
| EAQ63338.1 | EAQ66259.1 | MED121_03130 | MED121_06240 | Hypothetical protein; COG0637 Predicted phosphatase/phosphohexomutase. | Hypothetical protein; COG0637 Predicted phosphatase/phosphohexomutase. | 0.467 |
| EAQ63595.1 | EAQ63338.1 | MED121_00265 | MED121_03130 | Alpha-glucosidase; COG0366 Glycosidases. | Hypothetical protein; COG0637 Predicted phosphatase/phosphohexomutase. | 0.407 |
| EAQ63595.1 | EAQ63596.1 | MED121_00265 | MED121_00270 | Alpha-glucosidase; COG0366 Glycosidases. | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | 0.514 |
| EAQ63595.1 | EAQ66879.1 | MED121_00265 | MED121_13165 | Alpha-glucosidase; COG0366 Glycosidases. | COG0637 Predicted phosphatase/phosphohexomutase. | 0.437 |
| EAQ63596.1 | EAQ63338.1 | MED121_00270 | MED121_03130 | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein; COG0637 Predicted phosphatase/phosphohexomutase. | 0.686 |
| EAQ63596.1 | EAQ63595.1 | MED121_00270 | MED121_00265 | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | Alpha-glucosidase; COG0366 Glycosidases. | 0.514 |
| EAQ63596.1 | EAQ65445.1 | MED121_00270 | MED121_22277 | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.524 |
| EAQ63596.1 | EAQ65997.1 | MED121_00270 | MED121_02260 | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein. | 0.549 |
| EAQ63596.1 | EAQ66259.1 | MED121_00270 | MED121_06240 | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein; COG0637 Predicted phosphatase/phosphohexomutase. | 0.717 |
| EAQ63596.1 | EAQ66315.1 | MED121_00270 | MED121_06520 | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | Plasmid partition ParA protein. | 0.511 |
| EAQ63596.1 | EAQ66879.1 | MED121_00270 | MED121_13165 | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | COG0637 Predicted phosphatase/phosphohexomutase. | 0.631 |
| EAQ63596.1 | ndk | MED121_00270 | MED121_15679 | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.508 |
| EAQ63596.1 | thyA | MED121_00270 | MED121_19886 | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.500 |
| EAQ63596.1 | tmk | MED121_00270 | MED121_00050 | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.492 |
| EAQ65445.1 | EAQ63596.1 | MED121_22277 | MED121_00270 | Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Probable MFS metabolite transporter; COG0477 Permeases of the major facilitator superfamily. | 0.524 |
| EAQ65445.1 | ndk | MED121_22277 | MED121_15679 | Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.971 |
| EAQ65445.1 | thyA | MED121_22277 | MED121_19886 | Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.903 |
| EAQ65445.1 | tmk | MED121_22277 | MED121_00050 | Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.967 |