node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAQ64261.1 | EAQ65903.1 | MED121_19329 | MED121_01790 | Riboflavin biosynthesis protein RibD:Riboflavin-specific deaminase, C-terminal; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TopA protein; COG0551 Zn-finger domain associated with topoisomerase type I. | 0.566 |
EAQ64261.1 | EAQ65905.1 | MED121_19329 | MED121_01800 | Riboflavin biosynthesis protein RibD:Riboflavin-specific deaminase, C-terminal; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; COG1011 Predicted hydrolase (HAD superfamily). | 0.828 |
EAQ64261.1 | guaA | MED121_19329 | MED121_06590 | Riboflavin biosynthesis protein RibD:Riboflavin-specific deaminase, C-terminal; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.628 |
EAQ64261.1 | guaB | MED121_19329 | MED121_06600 | Riboflavin biosynthesis protein RibD:Riboflavin-specific deaminase, C-terminal; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.631 |
EAQ64261.1 | hemH | MED121_19329 | MED121_01805 | Riboflavin biosynthesis protein RibD:Riboflavin-specific deaminase, C-terminal; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.430 |
EAQ65566.1 | EAQ65567.1 | MED121_08378 | MED121_08383 | FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal; COG0277 FAD/FMN-containing dehydrogenases. | FAD linked oxidase; COG0277 FAD/FMN-containing dehydrogenases. | 0.998 |
EAQ65566.1 | EAQ65905.1 | MED121_08378 | MED121_01800 | FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal; COG0277 FAD/FMN-containing dehydrogenases. | Hypothetical protein; COG1011 Predicted hydrolase (HAD superfamily). | 0.528 |
EAQ65566.1 | EAQ66676.1 | MED121_08378 | MED121_12150 | FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal; COG0277 FAD/FMN-containing dehydrogenases. | Oxidoreductase, FAD-binding, putative; COG0277 FAD/FMN-containing dehydrogenases. | 0.801 |
EAQ65566.1 | EAQ66993.1 | MED121_08378 | MED121_13735 | FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal; COG0277 FAD/FMN-containing dehydrogenases. | Fe-S oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases. | 0.837 |
EAQ65567.1 | EAQ65566.1 | MED121_08383 | MED121_08378 | FAD linked oxidase; COG0277 FAD/FMN-containing dehydrogenases. | FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal; COG0277 FAD/FMN-containing dehydrogenases. | 0.998 |
EAQ65567.1 | EAQ65905.1 | MED121_08383 | MED121_01800 | FAD linked oxidase; COG0277 FAD/FMN-containing dehydrogenases. | Hypothetical protein; COG1011 Predicted hydrolase (HAD superfamily). | 0.528 |
EAQ65567.1 | EAQ66676.1 | MED121_08383 | MED121_12150 | FAD linked oxidase; COG0277 FAD/FMN-containing dehydrogenases. | Oxidoreductase, FAD-binding, putative; COG0277 FAD/FMN-containing dehydrogenases. | 0.801 |
EAQ65567.1 | EAQ66993.1 | MED121_08383 | MED121_13735 | FAD linked oxidase; COG0277 FAD/FMN-containing dehydrogenases. | Fe-S oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases. | 0.831 |
EAQ65903.1 | EAQ64261.1 | MED121_01790 | MED121_19329 | TopA protein; COG0551 Zn-finger domain associated with topoisomerase type I. | Riboflavin biosynthesis protein RibD:Riboflavin-specific deaminase, C-terminal; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.566 |
EAQ65903.1 | EAQ65904.1 | MED121_01790 | MED121_01795 | TopA protein; COG0551 Zn-finger domain associated with topoisomerase type I. | Hypothetical protein; COG2811 Archaeal/vacuolar-type H+-ATPase subunit H. | 0.737 |
EAQ65903.1 | EAQ65905.1 | MED121_01790 | MED121_01800 | TopA protein; COG0551 Zn-finger domain associated with topoisomerase type I. | Hypothetical protein; COG1011 Predicted hydrolase (HAD superfamily). | 0.699 |
EAQ65903.1 | guaA | MED121_01790 | MED121_06590 | TopA protein; COG0551 Zn-finger domain associated with topoisomerase type I. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.489 |
EAQ65903.1 | hemH | MED121_01790 | MED121_01805 | TopA protein; COG0551 Zn-finger domain associated with topoisomerase type I. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.781 |
EAQ65904.1 | EAQ65903.1 | MED121_01795 | MED121_01790 | Hypothetical protein; COG2811 Archaeal/vacuolar-type H+-ATPase subunit H. | TopA protein; COG0551 Zn-finger domain associated with topoisomerase type I. | 0.737 |
EAQ65904.1 | EAQ65905.1 | MED121_01795 | MED121_01800 | Hypothetical protein; COG2811 Archaeal/vacuolar-type H+-ATPase subunit H. | Hypothetical protein; COG1011 Predicted hydrolase (HAD superfamily). | 0.714 |