STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ66118.13-hydroxymethylglutaryl-CoA or malyl-CoA lyase; COG0119 Isopropylmalate/homocitrate/citramalate synthases. (314 aa)    
Predicted Functional Partners:
EAQ66116.1
Putative enoyl-CoA hydratase/isomerase; COG1024 Enoyl-CoA hydratase/carnithine racemase.
 
 0.997
EAQ66114.1
COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
 
 0.974
EAQ65743.1
3-oxoacid CoA-transferase; COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit.
  
 
 0.962
EAQ65742.1
3-oxoacid CoA-transferase subunit B family enzyme; COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit.
  
 
 0.961
fadA
acetyl-CoA C-acyltransferase FadA; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
 
 0.954
EAQ65116.1
Carbamoyl-phosphate synthase, putative; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.
 
 
 0.938
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.938
leuC
Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.937
leuD
Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
 
 0.937
EAQ63720.1
Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.931
Your Current Organism:
Marinomonas sp. MED121
NCBI taxonomy Id: 314277
Other names: M. sp. MED121
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