| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ63082.1 | EAQ64352.1 | MED121_19786 | MED121_04513 | COG0460 Homoserine dehydrogenase. | Membrane protein, putative; COG0477 Permeases of the major facilitator superfamily. | 0.569 |
| EAQ63082.1 | EAQ66667.1 | MED121_19786 | MED121_12105 | COG0460 Homoserine dehydrogenase. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase,repressor of metE and metF; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.987 |
| EAQ63082.1 | EAQ66938.1 | MED121_19786 | MED121_13460 | COG0460 Homoserine dehydrogenase. | Chorismate mutase/prephenate dehydrogenase; COG1605 Chorismate mutase. | 0.904 |
| EAQ63720.1 | EAQ63722.1 | MED121_03447 | MED121_03457 | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | 0.999 |
| EAQ63720.1 | EAQ64104.1 | MED121_03447 | MED121_00690 | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.999 |
| EAQ63720.1 | EAQ64352.1 | MED121_03447 | MED121_04513 | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Membrane protein, putative; COG0477 Permeases of the major facilitator superfamily. | 0.745 |
| EAQ63720.1 | EAQ66667.1 | MED121_03447 | MED121_12105 | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase,repressor of metE and metF; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.836 |
| EAQ63720.1 | EAQ66680.1 | MED121_03447 | MED121_12170 | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 2,3-dihydroxybenzoate--[carrier protein] ligase (enterobactin synthetase component E); COG1021 Peptide arylation enzymes. | 0.999 |
| EAQ63720.1 | EAQ66839.1 | MED121_03447 | MED121_12965 | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.680 |
| EAQ63720.1 | EAQ66938.1 | MED121_03447 | MED121_13460 | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Chorismate mutase/prephenate dehydrogenase; COG1605 Chorismate mutase. | 0.770 |
| EAQ63722.1 | EAQ63720.1 | MED121_03457 | MED121_03447 | Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 0.999 |
| EAQ63722.1 | EAQ64104.1 | MED121_03457 | MED121_00690 | Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.999 |
| EAQ63722.1 | EAQ64352.1 | MED121_03457 | MED121_04513 | Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | Membrane protein, putative; COG0477 Permeases of the major facilitator superfamily. | 0.699 |
| EAQ63722.1 | EAQ66667.1 | MED121_03457 | MED121_12105 | Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase,repressor of metE and metF; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.681 |
| EAQ63722.1 | EAQ66680.1 | MED121_03457 | MED121_12170 | Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | 2,3-dihydroxybenzoate--[carrier protein] ligase (enterobactin synthetase component E); COG1021 Peptide arylation enzymes. | 0.999 |
| EAQ63722.1 | EAQ66839.1 | MED121_03457 | MED121_12965 | Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.507 |
| EAQ63722.1 | EAQ66938.1 | MED121_03457 | MED121_13460 | Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | Chorismate mutase/prephenate dehydrogenase; COG1605 Chorismate mutase. | 0.843 |
| EAQ64104.1 | EAQ63720.1 | MED121_00690 | MED121_03447 | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family. | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 0.999 |
| EAQ64104.1 | EAQ63722.1 | MED121_00690 | MED121_03457 | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family. | Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | 0.999 |
| EAQ64104.1 | EAQ64352.1 | MED121_00690 | MED121_04513 | Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family. | Membrane protein, putative; COG0477 Permeases of the major facilitator superfamily. | 0.540 |