| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ63113.1 | EAQ63809.1 | MED121_23755 | MED121_05463 | Hypothetical protein. | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.993 |
| EAQ63113.1 | EAQ64508.1 | MED121_23755 | MED121_21195 | Hypothetical protein. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.501 |
| EAQ63113.1 | EAQ65421.1 | MED121_23755 | MED121_22157 | Hypothetical protein. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.468 |
| EAQ63113.1 | EAQ67301.1 | MED121_23755 | MED121_15279 | Hypothetical protein. | uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.560 |
| EAQ63113.1 | EAQ67354.1 | MED121_23755 | MED121_15544 | Hypothetical protein. | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | 0.979 |
| EAQ63113.1 | EAQ67355.1 | MED121_23755 | MED121_15549 | Hypothetical protein. | precorrin-6Y C5,15-methyltransferase (decarboxylating); COG2241 Precorrin-6B methylase 1. | 0.965 |
| EAQ63113.1 | cysD | MED121_23755 | MED121_03788 | Hypothetical protein. | Sulfate adenylyltransferase, subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. | 0.468 |
| EAQ63809.1 | EAQ63113.1 | MED121_05463 | MED121_23755 | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Hypothetical protein. | 0.993 |
| EAQ63809.1 | EAQ64508.1 | MED121_05463 | MED121_21195 | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.987 |
| EAQ63809.1 | EAQ65421.1 | MED121_05463 | MED121_22157 | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.983 |
| EAQ63809.1 | EAQ65670.1 | MED121_05463 | MED121_08898 | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 5-aminolevulinate dehydratase (porphobilinogen synthase); COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.989 |
| EAQ63809.1 | EAQ65902.1 | MED121_05463 | MED121_01785 | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Cobalamin (vitamin B12) biosynthesis CbiX protein. | 0.993 |
| EAQ63809.1 | EAQ67301.1 | MED121_05463 | MED121_15279 | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.967 |
| EAQ63809.1 | EAQ67354.1 | MED121_05463 | MED121_15544 | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | 0.976 |
| EAQ63809.1 | EAQ67355.1 | MED121_05463 | MED121_15549 | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | precorrin-6Y C5,15-methyltransferase (decarboxylating); COG2241 Precorrin-6B methylase 1. | 0.972 |
| EAQ63809.1 | cysD | MED121_05463 | MED121_03788 | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Sulfate adenylyltransferase, subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. | 0.975 |
| EAQ63809.1 | hemC | MED121_05463 | MED121_15274 | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| EAQ64508.1 | EAQ63113.1 | MED121_21195 | MED121_23755 | COG0155 Sulfite reductase, beta subunit (hemoprotein). | Hypothetical protein. | 0.501 |
| EAQ64508.1 | EAQ63809.1 | MED121_21195 | MED121_05463 | COG0155 Sulfite reductase, beta subunit (hemoprotein). | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.987 |
| EAQ64508.1 | EAQ65421.1 | MED121_21195 | MED121_22157 | COG0155 Sulfite reductase, beta subunit (hemoprotein). | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.999 |