STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ66195.1Hypothetical protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (58 aa)    
Predicted Functional Partners:
ccmC
Cytochrome c-type biogenesis protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
  
 
 0.996
EAQ66197.1
Putative heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
  
 
 0.988
ccmE
CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
  
 
 0.971
EAQ66198.1
Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
   
 
 0.959
EAQ66193.1
Cytochrome C-type biogenesis protein CcmF; COG1138 Cytochrome c biogenesis factor.
  
  
 0.862
EAQ66192.1
Thiol:disulfide interchange protein DsbE; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
  
 0.812
EAQ66191.1
Cytochrome c-type biogenesis protein CcmH; Possible subunit of a heme lyase.
  
  
 0.765
EAQ66190.1
COG4235 Cytochrome c biogenesis factor.
  
  
 0.717
EAQ66199.1
COG3210 Large exoproteins involved in heme utilization or adhesion.
       0.496
EAQ66200.1
FlhB domain protein; COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB.
       0.496
Your Current Organism:
Marinomonas sp. MED121
NCBI taxonomy Id: 314277
Other names: M. sp. MED121
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