STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folE2Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. (316 aa)    
Predicted Functional Partners:
EAQ67275.1
Serine/threonine kinase with two-component sensor domain; COG0642 Signal transduction histidine kinase.
    
  0.927
folE
COG0302 GTP cyclohydrolase I.
     
 0.885
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.869
EAQ64527.1
Serine/Threonine protein kinase and Signal Transduction Histidine Kinase (STHK) with GAF sensor; COG0642 Signal transduction histidine kinase.
    
  0.849
EAQ65817.1
COG0515 Serine/threonine protein kinase.
    
  0.843
EAQ64979.1
Diguanylate cyclase (GGDEF domain) with PAS/PAC sensor; COG2199 FOG: GGDEF domain.
   
 
  0.830
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
     
 0.797
EAQ65142.1
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
 
  
  0.786
EAQ66105.1
Probable sensory transduction system regulatory protein; COG2199 FOG: GGDEF domain.
    
  0.758
EAQ67304.1
Probable sensor/response regulator hybrid; COG0642 Signal transduction histidine kinase.
    
  0.757
Your Current Organism:
Marinomonas sp. MED121
NCBI taxonomy Id: 314277
Other names: M. sp. MED121
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.