STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ65602.1Chaperone protein dnaJ (Heat shock protein J) (HSP40), co-chaperone with DnaK; COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain. (131 aa)    
Predicted Functional Partners:
EAQ65603.1
COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain.
     0.993
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 0.991
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
 
 
 0.983
htpG
Heat shock protein HtpG; Molecular chaperone. Has ATPase activity.
 
 0.967
EAQ63720.1
Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
   
 
 0.963
EAQ64104.1
Amino acid adenylation; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.939
EAQ63722.1
Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
   
 
 0.939
groL
Chaperonin, 60 Kd subunit; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
 0.926
EAQ66100.1
Hypothetical protein.
  
 0.925
EAQ64126.1
Heat shock protein 70; COG0443 Molecular chaperone.
  
 0.916
Your Current Organism:
Marinomonas sp. MED121
NCBI taxonomy Id: 314277
Other names: M. sp. MED121
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.