| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ63398.1 | EAQ63399.1 | MED121_23790 | MED121_23795 | Precorrin-4 C11-methyltransferase region; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | Precorrin-3B C17-methyltransferase region; COG1010 Precorrin-3B methylase. | 0.999 |
| EAQ63398.1 | EAQ65487.1 | MED121_23790 | MED121_22487 | Precorrin-4 C11-methyltransferase region; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.613 |
| EAQ63398.1 | EAQ65658.1 | MED121_23790 | MED121_08838 | Precorrin-4 C11-methyltransferase region; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.912 |
| EAQ63398.1 | EAQ65659.1 | MED121_23790 | MED121_08843 | Precorrin-4 C11-methyltransferase region; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthetic protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.485 |
| EAQ63398.1 | EAQ66665.1 | MED121_23790 | MED121_12095 | Precorrin-4 C11-methyltransferase region; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.609 |
| EAQ63398.1 | EAQ67354.1 | MED121_23790 | MED121_15544 | Precorrin-4 C11-methyltransferase region; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | 0.981 |
| EAQ63398.1 | EAQ67356.1 | MED121_23790 | MED121_15554 | Precorrin-4 C11-methyltransferase region; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | precorrin-8X methylmutase; COG2082 Precorrin isomerase. | 0.991 |
| EAQ63398.1 | EAQ67359.1 | MED121_23790 | MED121_15569 | Precorrin-4 C11-methyltransferase region; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | COG1797 Cobyrinic acid a,c-diamide synthase. | 0.921 |
| EAQ63398.1 | cobD | MED121_23790 | MED121_08848 | Precorrin-4 C11-methyltransferase region; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.917 |
| EAQ63398.1 | cobQ | MED121_23790 | MED121_08853 | Precorrin-4 C11-methyltransferase region; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.967 |
| EAQ63399.1 | EAQ63398.1 | MED121_23795 | MED121_23790 | Precorrin-3B C17-methyltransferase region; COG1010 Precorrin-3B methylase. | Precorrin-4 C11-methyltransferase region; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family. | 0.999 |
| EAQ63399.1 | EAQ65487.1 | MED121_23795 | MED121_22487 | Precorrin-3B C17-methyltransferase region; COG1010 Precorrin-3B methylase. | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.655 |
| EAQ63399.1 | EAQ65658.1 | MED121_23795 | MED121_08838 | Precorrin-3B C17-methyltransferase region; COG1010 Precorrin-3B methylase. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.802 |
| EAQ63399.1 | EAQ65659.1 | MED121_23795 | MED121_08843 | Precorrin-3B C17-methyltransferase region; COG1010 Precorrin-3B methylase. | Cobalamin biosynthetic protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.515 |
| EAQ63399.1 | EAQ66665.1 | MED121_23795 | MED121_12095 | Precorrin-3B C17-methyltransferase region; COG1010 Precorrin-3B methylase. | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.641 |
| EAQ63399.1 | EAQ67354.1 | MED121_23795 | MED121_15544 | Precorrin-3B C17-methyltransferase region; COG1010 Precorrin-3B methylase. | COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family. | 0.999 |
| EAQ63399.1 | EAQ67356.1 | MED121_23795 | MED121_15554 | Precorrin-3B C17-methyltransferase region; COG1010 Precorrin-3B methylase. | precorrin-8X methylmutase; COG2082 Precorrin isomerase. | 0.994 |
| EAQ63399.1 | EAQ67359.1 | MED121_23795 | MED121_15569 | Precorrin-3B C17-methyltransferase region; COG1010 Precorrin-3B methylase. | COG1797 Cobyrinic acid a,c-diamide synthase. | 0.926 |
| EAQ63399.1 | cobD | MED121_23795 | MED121_08848 | Precorrin-3B C17-methyltransferase region; COG1010 Precorrin-3B methylase. | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.922 |
| EAQ63399.1 | cobQ | MED121_23795 | MED121_08853 | Precorrin-3B C17-methyltransferase region; COG1010 Precorrin-3B methylase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.992 |