STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (775 aa)    
Predicted Functional Partners:
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
 0.950
EAQ65668.1
COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family.
 
  
 0.915
EAQ64827.1
Membrane protein component of ABC phosphate transporter; COG4985 ABC-type phosphate transport system, auxiliary component.
     
 0.609
EAQ65670.1
5-aminolevulinate dehydratase (porphobilinogen synthase); COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
    0.591
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.591
gph
COG0546 Predicted phosphatases.
  
 
 0.522
rpmI
COG0291 Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
   
   0.477
EAQ65134.1
Histidinol-phosphate phosphatase family protein; COG0241 Histidinol phosphatase and related phosphatases.
    
   0.472
EAQ67440.1
Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein.
    
  0.461
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.460
Your Current Organism:
Marinomonas sp. MED121
NCBI taxonomy Id: 314277
Other names: M. sp. MED121
Server load: medium (76%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.