STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metXSHomoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (389 aa)    
Predicted Functional Partners:
EAQ64931.1
Methionine biosynthesis protein MetW; COG0500 SAM-dependent methyltransferases.
  
 0.998
EAQ63211.1
COG2873 O-acetylhomoserine sulfhydrylase.
 
 
 0.991
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
  
 0.968
EAQ66667.1
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase,repressor of metE and metF; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.966
EAQ63082.1
COG0460 Homoserine dehydrogenase.
 
 0.955
EAQ64484.1
COG0112 Glycine/serine hydroxymethyltransferase.
     
 0.885
EAQ67496.1
COG0560 Phosphoserine phosphatase.
     
 0.867
EAQ65999.1
Methionine gamma-lyase; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
 
  
 0.866
EAQ64930.1
Uncharacterized conserved secreted protein.
       0.829
EAQ64929.1
Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.805
Your Current Organism:
Marinomonas sp. MED121
NCBI taxonomy Id: 314277
Other names: M. sp. MED121
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