node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAQ64493.1 | EAQ65032.1 | MED121_21120 | MED121_09940 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | COG1145 Ferredoxin. | 0.934 |
EAQ64493.1 | EAQ65551.1 | MED121_21120 | MED121_22807 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.941 |
EAQ64493.1 | EAQ66827.1 | MED121_21120 | MED121_12905 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. | 0.968 |
EAQ64493.1 | EAQ66828.1 | MED121_21120 | MED121_12910 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.674 |
EAQ64493.1 | EAQ66829.1 | MED121_21120 | MED121_12915 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.736 |
EAQ64493.1 | EAQ66830.1 | MED121_21120 | MED121_12920 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.868 |
EAQ64493.1 | EAQ67697.1 | MED121_21120 | MED121_17259 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.674 |
EAQ64493.1 | sucC | MED121_21120 | MED121_12880 | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.622 |
EAQ64495.1 | EAQ65032.1 | MED121_21130 | MED121_09940 | Probable fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | COG1145 Ferredoxin. | 0.808 |
EAQ64495.1 | EAQ65551.1 | MED121_21130 | MED121_22807 | Probable fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.818 |
EAQ64495.1 | EAQ66827.1 | MED121_21130 | MED121_12905 | Probable fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. | 0.995 |
EAQ64495.1 | EAQ66828.1 | MED121_21130 | MED121_12910 | Probable fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.996 |
EAQ64495.1 | EAQ66829.1 | MED121_21130 | MED121_12915 | Probable fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.990 |
EAQ64495.1 | EAQ66830.1 | MED121_21130 | MED121_12920 | Probable fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.989 |
EAQ64495.1 | EAQ67697.1 | MED121_21130 | MED121_17259 | Probable fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Hypothetical protein; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.987 |
EAQ64495.1 | sucC | MED121_21130 | MED121_12880 | Probable fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.960 |
EAQ64495.1 | sucD | MED121_21130 | MED121_12875 | Probable fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.941 |
EAQ65032.1 | EAQ64493.1 | MED121_09940 | MED121_21120 | COG1145 Ferredoxin. | Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). | 0.934 |
EAQ65032.1 | EAQ64495.1 | MED121_09940 | MED121_21130 | COG1145 Ferredoxin. | Probable fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.808 |
EAQ65032.1 | EAQ65551.1 | MED121_09940 | MED121_22807 | COG1145 Ferredoxin. | COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.998 |