| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ63434.1 | EAQ67052.1 | MED121_23970 | MED121_14030 | Probable hydratase; COG0388 Predicted amidohydrolase. | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.761 |
| EAQ63434.1 | EAQ67054.1 | MED121_23970 | MED121_14040 | Probable hydratase; COG0388 Predicted amidohydrolase. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.878 |
| EAQ63434.1 | carB | MED121_23970 | MED121_19199 | Probable hydratase; COG0388 Predicted amidohydrolase. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.449 |
| EAQ63434.1 | pyrB | MED121_23970 | MED121_09975 | Probable hydratase; COG0388 Predicted amidohydrolase. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.461 |
| EAQ63434.1 | pyrD | MED121_23970 | MED121_23299 | Probable hydratase; COG0388 Predicted amidohydrolase. | Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.593 |
| EAQ65040.1 | EAQ67054.1 | MED121_09980 | MED121_14040 | COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.943 |
| EAQ65040.1 | carA | MED121_09980 | MED121_19204 | COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.862 |
| EAQ65040.1 | carB | MED121_09980 | MED121_19199 | COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.930 |
| EAQ65040.1 | pyrB | MED121_09980 | MED121_09975 | COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.997 |
| EAQ65040.1 | pyrD | MED121_09980 | MED121_23299 | COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.908 |
| EAQ65040.1 | pyrE | MED121_09980 | MED121_09645 | COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.957 |
| EAQ65040.1 | pyrF | MED121_09980 | MED121_05253 | COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.994 |
| EAQ67052.1 | EAQ63434.1 | MED121_14030 | MED121_23970 | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | Probable hydratase; COG0388 Predicted amidohydrolase. | 0.761 |
| EAQ67052.1 | EAQ67053.1 | MED121_14030 | MED121_14035 | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | Transporter, NCS1 nucleoside family protein; COG1953 Cytosine/uracil/thiamine/allantoin permeases. | 0.877 |
| EAQ67052.1 | EAQ67054.1 | MED121_14030 | MED121_14040 | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.988 |
| EAQ67052.1 | carB | MED121_14030 | MED121_19199 | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.525 |
| EAQ67052.1 | pyrD | MED121_14030 | MED121_23299 | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.651 |
| EAQ67053.1 | EAQ67052.1 | MED121_14035 | MED121_14030 | Transporter, NCS1 nucleoside family protein; COG1953 Cytosine/uracil/thiamine/allantoin permeases. | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.877 |
| EAQ67053.1 | EAQ67054.1 | MED121_14035 | MED121_14040 | Transporter, NCS1 nucleoside family protein; COG1953 Cytosine/uracil/thiamine/allantoin permeases. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.939 |
| EAQ67054.1 | EAQ63434.1 | MED121_14040 | MED121_23970 | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Probable hydratase; COG0388 Predicted amidohydrolase. | 0.878 |