| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ63774.1 | EAQ64882.1 | MED121_05288 | MED121_10979 | COG0524 Sugar kinases, ribokinase family. | Predicted protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.937 |
| EAQ63774.1 | EAQ65239.1 | MED121_05288 | MED121_18400 | COG0524 Sugar kinases, ribokinase family. | COG0572 Uridine kinase. | 0.420 |
| EAQ63774.1 | EAQ67306.1 | MED121_05288 | MED121_15304 | COG0524 Sugar kinases, ribokinase family. | Nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | 0.955 |
| EAQ63774.1 | cpdB | MED121_05288 | MED121_19579 | COG0524 Sugar kinases, ribokinase family. | 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.925 |
| EAQ63774.1 | guaA | MED121_05288 | MED121_06590 | COG0524 Sugar kinases, ribokinase family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.939 |
| EAQ63774.1 | guaB | MED121_05288 | MED121_06600 | COG0524 Sugar kinases, ribokinase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.930 |
| EAQ63774.1 | purA | MED121_05288 | MED121_20391 | COG0524 Sugar kinases, ribokinase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.968 |
| EAQ63774.1 | surE | MED121_05288 | MED121_16284 | COG0524 Sugar kinases, ribokinase family. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.923 |
| EAQ64882.1 | EAQ63774.1 | MED121_10979 | MED121_05288 | Predicted protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | COG0524 Sugar kinases, ribokinase family. | 0.937 |
| EAQ64882.1 | EAQ65239.1 | MED121_10979 | MED121_18400 | Predicted protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | COG0572 Uridine kinase. | 0.947 |
| EAQ64882.1 | EAQ67306.1 | MED121_10979 | MED121_15304 | Predicted protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | 0.940 |
| EAQ64882.1 | cpdB | MED121_10979 | MED121_19579 | Predicted protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.941 |
| EAQ64882.1 | guaA | MED121_10979 | MED121_06590 | Predicted protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.928 |
| EAQ64882.1 | guaB | MED121_10979 | MED121_06600 | Predicted protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.961 |
| EAQ64882.1 | purA | MED121_10979 | MED121_20391 | Predicted protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.929 |
| EAQ64882.1 | surE | MED121_10979 | MED121_16284 | Predicted protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.932 |
| EAQ65040.1 | EAQ65239.1 | MED121_09980 | MED121_18400 | COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | COG0572 Uridine kinase. | 0.936 |
| EAQ65040.1 | EAQ67306.1 | MED121_09980 | MED121_15304 | COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | Nucleotidase; COG1011 Predicted hydrolase (HAD superfamily). | 0.931 |
| EAQ65040.1 | guaA | MED121_09980 | MED121_06590 | COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.514 |
| EAQ65040.1 | guaB | MED121_09980 | MED121_06600 | COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.418 |