| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ63826.1 | EAQ64743.1 | MED121_05548 | MED121_23379 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase. | 0.557 |
| EAQ63826.1 | EAQ67450.1 | MED121_05548 | MED121_16024 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.557 |
| EAQ63826.1 | EAQ67548.1 | MED121_05548 | MED121_16514 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | MazG family protein; COG1694 Predicted pyrophosphatase. | 0.924 |
| EAQ63826.1 | adk | MED121_05548 | MED121_16504 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.981 |
| EAQ63826.1 | apt | MED121_05548 | MED121_01720 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.983 |
| EAQ63826.1 | ndk | MED121_05548 | MED121_15679 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.486 |
| EAQ64743.1 | EAQ63826.1 | MED121_23379 | MED121_05548 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase. | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.557 |
| EAQ64743.1 | EAQ65142.1 | MED121_23379 | MED121_17915 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.470 |
| EAQ64743.1 | EAQ65445.1 | MED121_23379 | MED121_22277 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase. | Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.516 |
| EAQ64743.1 | EAQ65446.1 | MED121_23379 | MED121_22282 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase. | COG0208 Ribonucleotide reductase, beta subunit. | 0.509 |
| EAQ64743.1 | EAQ67548.1 | MED121_23379 | MED121_16514 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase. | MazG family protein; COG1694 Predicted pyrophosphatase. | 0.753 |
| EAQ64743.1 | adk | MED121_23379 | MED121_16504 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.936 |
| EAQ64743.1 | apt | MED121_23379 | MED121_01720 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.796 |
| EAQ64743.1 | ndk | MED121_23379 | MED121_15679 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase. | Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.546 |
| EAQ65142.1 | EAQ64743.1 | MED121_17915 | MED121_23379 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase. | 0.470 |
| EAQ65142.1 | EAQ65445.1 | MED121_17915 | MED121_22277 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.931 |
| EAQ65142.1 | EAQ65446.1 | MED121_17915 | MED121_22282 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | COG0208 Ribonucleotide reductase, beta subunit. | 0.935 |
| EAQ65142.1 | EAQ67450.1 | MED121_17915 | MED121_16024 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.470 |
| EAQ65142.1 | adk | MED121_17915 | MED121_16504 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.932 |
| EAQ65142.1 | ndk | MED121_17915 | MED121_15679 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.931 |