STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ64279.1COG1785 Alkaline phosphatase; Belongs to the alkaline phosphatase family. (525 aa)    
Predicted Functional Partners:
secA
Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
    
 
 0.879
EAQ63204.1
Hypothetical protein; COG3540 Phosphodiesterase/alkaline phosphatase D.
  
 
 0.869
secB
Export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
    
 
 0.869
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
    
 
 0.865
EAQ64099.1
Hypothetical protein.
    
 
 0.828
EAQ64126.1
Heat shock protein 70; COG0443 Molecular chaperone.
 
 
 
 0.748
EAQ64127.1
Heat shock protein 70; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family.
 
 
 
 0.748
folE
COG0302 GTP cyclohydrolase I.
   
 
  0.739
EAQ64827.1
Membrane protein component of ABC phosphate transporter; COG4985 ABC-type phosphate transport system, auxiliary component.
  
  
 0.726
EAQ66927.1
Hypothetical protein.
  
 
 0.723
Your Current Organism:
Marinomonas sp. MED121
NCBI taxonomy Id: 314277
Other names: M. sp. MED121
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.