STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ63083.1COG0498 Threonine synthase. (461 aa)    
Predicted Functional Partners:
EAQ63082.1
COG0460 Homoserine dehydrogenase.
 
 0.997
thrB
Ketohexokinase; COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family.
    
 0.968
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
   
 0.964
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
    
 0.929
EAQ63012.1
COG1171 Threonine dehydratase.
  
 
 0.925
EAQ63875.1
Putative low specificity l-threonine aldolase protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
 
 0.894
EAQ63585.1
Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family.
  
 
 0.893
leuD
Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
  
 0.868
EAQ63217.1
Putative threonine dehydratase, catabolic; COG1171 Threonine dehydratase.
  
 
 0.856
EAQ63167.1
COG1171 Threonine dehydratase.
  
 
 0.856
Your Current Organism:
Marinomonas sp. MED121
NCBI taxonomy Id: 314277
Other names: M. sp. MED121
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