| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ63507.1 | EAQ63508.1 | MED121_19871 | MED121_19876 | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | 0.827 |
| EAQ63507.1 | EAQ63588.1 | MED121_19871 | MED121_00230 | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. | Sensory box protein; COG2202 FOG: PAS/PAC domain. | 0.470 |
| EAQ63507.1 | EAQ66667.1 | MED121_19871 | MED121_12105 | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase,repressor of metE and metF; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.722 |
| EAQ63507.1 | lgt | MED121_19871 | MED121_19881 | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.530 |
| EAQ63508.1 | EAQ63507.1 | MED121_19876 | MED121_19871 | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. | 0.827 |
| EAQ63508.1 | EAQ63588.1 | MED121_19876 | MED121_00230 | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | Sensory box protein; COG2202 FOG: PAS/PAC domain. | 0.489 |
| EAQ63508.1 | EAQ63809.1 | MED121_19876 | MED121_05463 | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.584 |
| EAQ63508.1 | EAQ65377.1 | MED121_19876 | MED121_21937 | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | Nitrogen regulatory IIA protein PtsN; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | 0.788 |
| EAQ63508.1 | EAQ65378.1 | MED121_19876 | MED121_21942 | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | PtsH; COG1925 Phosphotransferase system, HPr-related proteins. | 0.992 |
| EAQ63508.1 | EAQ65794.1 | MED121_19876 | MED121_09518 | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | GGDEF domain protein; COG2203 FOG: GAF domain. | 0.490 |
| EAQ63508.1 | EAQ65896.1 | MED121_19876 | MED121_01755 | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | Response regulator of sigma subunit, serine phosphatase (CheY-RsbU); COG0784 FOG: CheY-like receiver. | 0.514 |
| EAQ63508.1 | EAQ66054.1 | MED121_19876 | MED121_02545 | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | Sensory box/GGDEF/EAL domain protein; COG2202 FOG: PAS/PAC domain. | 0.490 |
| EAQ63508.1 | EAQ66667.1 | MED121_19876 | MED121_12105 | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase,repressor of metE and metF; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.743 |
| EAQ63508.1 | lgt | MED121_19876 | MED121_19881 | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.577 |
| EAQ63588.1 | EAQ63507.1 | MED121_00230 | MED121_19871 | Sensory box protein; COG2202 FOG: PAS/PAC domain. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. | 0.470 |
| EAQ63588.1 | EAQ63508.1 | MED121_00230 | MED121_19876 | Sensory box protein; COG2202 FOG: PAS/PAC domain. | Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. | 0.489 |
| EAQ63588.1 | EAQ65794.1 | MED121_00230 | MED121_09518 | Sensory box protein; COG2202 FOG: PAS/PAC domain. | GGDEF domain protein; COG2203 FOG: GAF domain. | 0.986 |
| EAQ63588.1 | EAQ65896.1 | MED121_00230 | MED121_01755 | Sensory box protein; COG2202 FOG: PAS/PAC domain. | Response regulator of sigma subunit, serine phosphatase (CheY-RsbU); COG0784 FOG: CheY-like receiver. | 0.969 |
| EAQ63588.1 | EAQ66054.1 | MED121_00230 | MED121_02545 | Sensory box protein; COG2202 FOG: PAS/PAC domain. | Sensory box/GGDEF/EAL domain protein; COG2202 FOG: PAS/PAC domain. | 0.986 |
| EAQ63588.1 | EAQ66667.1 | MED121_00230 | MED121_12105 | Sensory box protein; COG2202 FOG: PAS/PAC domain. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase,repressor of metE and metF; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.746 |