| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ64261.1 | EAQ64498.1 | MED121_19329 | MED121_21145 | Riboflavin biosynthesis protein RibD:Riboflavin-specific deaminase, C-terminal; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.544 |
| EAQ64261.1 | proS | MED121_19329 | MED121_21155 | Riboflavin biosynthesis protein RibD:Riboflavin-specific deaminase, C-terminal; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.423 |
| EAQ64497.1 | EAQ64498.1 | MED121_21140 | MED121_21145 | Hypothetical protein; COG1196 Chromosome segregation ATPases. | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.510 |
| EAQ64497.1 | EAQ64499.1 | MED121_21140 | MED121_21150 | Hypothetical protein; COG1196 Chromosome segregation ATPases. | Putative cytoplasmic protein; COG3386 Gluconolactonase. | 0.453 |
| EAQ64498.1 | EAQ64261.1 | MED121_21145 | MED121_19329 | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Riboflavin biosynthesis protein RibD:Riboflavin-specific deaminase, C-terminal; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.544 |
| EAQ64498.1 | EAQ64497.1 | MED121_21145 | MED121_21140 | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Hypothetical protein; COG1196 Chromosome segregation ATPases. | 0.510 |
| EAQ64498.1 | EAQ64499.1 | MED121_21145 | MED121_21150 | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Putative cytoplasmic protein; COG3386 Gluconolactonase. | 0.578 |
| EAQ64498.1 | EAQ66220.1 | MED121_21145 | MED121_06045 | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | 0.661 |
| EAQ64498.1 | EAQ66230.1 | MED121_21145 | MED121_06095 | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | 0.661 |
| EAQ64498.1 | EAQ66414.1 | MED121_21145 | MED121_07015 | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | COG1256 Flagellar hook-associated protein. | 0.661 |
| EAQ64498.1 | EAQ67541.1 | MED121_21145 | MED121_16479 | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | SlyX; COG2900 Uncharacterized protein conserved in bacteria. | 0.568 |
| EAQ64498.1 | apaH | MED121_21145 | MED121_07515 | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.458 |
| EAQ64498.1 | msrP | MED121_21145 | MED121_16129 | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S- [...] | 0.535 |
| EAQ64498.1 | proS | MED121_21145 | MED121_21155 | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.539 |
| EAQ64499.1 | EAQ64497.1 | MED121_21150 | MED121_21140 | Putative cytoplasmic protein; COG3386 Gluconolactonase. | Hypothetical protein; COG1196 Chromosome segregation ATPases. | 0.453 |
| EAQ64499.1 | EAQ64498.1 | MED121_21150 | MED121_21145 | Putative cytoplasmic protein; COG3386 Gluconolactonase. | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.578 |
| EAQ64499.1 | proS | MED121_21150 | MED121_21155 | Putative cytoplasmic protein; COG3386 Gluconolactonase. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.671 |
| EAQ66220.1 | EAQ64498.1 | MED121_06045 | MED121_21145 | Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | Histidine triad family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.661 |
| EAQ66220.1 | EAQ66230.1 | MED121_06045 | MED121_06095 | Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | 0.999 |
| EAQ66220.1 | EAQ66414.1 | MED121_06045 | MED121_07015 | Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | COG1256 Flagellar hook-associated protein. | 0.988 |