node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAQ63091.1 | EAQ65140.1 | MED121_10489 | MED121_10480 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Chromosomal replication initiator protein, DnaA; COG0593 ATPase involved in DNA replication initiation. | 0.976 |
EAQ63091.1 | gmhA | MED121_10489 | MED121_21800 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | COG0279 Phosphoheptose isomerase. | 0.716 |
EAQ64627.1 | EAQ64628.1 | MED121_21790 | MED121_21795 | COG3107 Putative lipoprotein. | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | 0.846 |
EAQ64627.1 | gmhA | MED121_21790 | MED121_21800 | COG3107 Putative lipoprotein. | COG0279 Phosphoheptose isomerase. | 0.876 |
EAQ64628.1 | EAQ64627.1 | MED121_21795 | MED121_21790 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | COG3107 Putative lipoprotein. | 0.846 |
EAQ64628.1 | gmhA | MED121_21795 | MED121_21800 | Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family. | COG0279 Phosphoheptose isomerase. | 0.893 |
EAQ64977.1 | gmhA | MED121_09665 | MED121_21800 | Response regulator; COG0784 FOG: CheY-like receiver. | COG0279 Phosphoheptose isomerase. | 0.704 |
EAQ65134.1 | EAQ66265.1 | MED121_10450 | MED121_06270 | Histidinol-phosphate phosphatase family protein; COG0241 Histidinol phosphatase and related phosphatases. | ADP-heptose-LPS heptosyltransferase II; COG0859 ADP-heptose:LPS heptosyltransferase. | 0.930 |
EAQ65134.1 | EAQ67075.1 | MED121_10450 | MED121_14149 | Histidinol-phosphate phosphatase family protein; COG0241 Histidinol phosphatase and related phosphatases. | Lipopolysaccharide biosynthesis protein; COG0859 ADP-heptose:LPS heptosyltransferase. | 0.891 |
EAQ65134.1 | gmhA | MED121_10450 | MED121_21800 | Histidinol-phosphate phosphatase family protein; COG0241 Histidinol phosphatase and related phosphatases. | COG0279 Phosphoheptose isomerase. | 0.986 |
EAQ65134.1 | hldD | MED121_10450 | MED121_06265 | Histidinol-phosphate phosphatase family protein; COG0241 Histidinol phosphatase and related phosphatases. | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.831 |
EAQ65134.1 | hldE | MED121_10450 | MED121_06255 | Histidinol-phosphate phosphatase family protein; COG0241 Histidinol phosphatase and related phosphatases. | LPS biosynthesis protein RfaE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.994 |
EAQ65140.1 | EAQ63091.1 | MED121_10480 | MED121_10489 | Chromosomal replication initiator protein, DnaA; COG0593 ATPase involved in DNA replication initiation. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.976 |
EAQ65140.1 | gmhA | MED121_10480 | MED121_21800 | Chromosomal replication initiator protein, DnaA; COG0593 ATPase involved in DNA replication initiation. | COG0279 Phosphoheptose isomerase. | 0.716 |
EAQ66265.1 | EAQ65134.1 | MED121_06270 | MED121_10450 | ADP-heptose-LPS heptosyltransferase II; COG0859 ADP-heptose:LPS heptosyltransferase. | Histidinol-phosphate phosphatase family protein; COG0241 Histidinol phosphatase and related phosphatases. | 0.930 |
EAQ66265.1 | EAQ67075.1 | MED121_06270 | MED121_14149 | ADP-heptose-LPS heptosyltransferase II; COG0859 ADP-heptose:LPS heptosyltransferase. | Lipopolysaccharide biosynthesis protein; COG0859 ADP-heptose:LPS heptosyltransferase. | 0.962 |
EAQ66265.1 | gmhA | MED121_06270 | MED121_21800 | ADP-heptose-LPS heptosyltransferase II; COG0859 ADP-heptose:LPS heptosyltransferase. | COG0279 Phosphoheptose isomerase. | 0.874 |
EAQ66265.1 | hldD | MED121_06270 | MED121_06265 | ADP-heptose-LPS heptosyltransferase II; COG0859 ADP-heptose:LPS heptosyltransferase. | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.975 |
EAQ66265.1 | hldE | MED121_06270 | MED121_06255 | ADP-heptose-LPS heptosyltransferase II; COG0859 ADP-heptose:LPS heptosyltransferase. | LPS biosynthesis protein RfaE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.957 |
EAQ67075.1 | EAQ65134.1 | MED121_14149 | MED121_10450 | Lipopolysaccharide biosynthesis protein; COG0859 ADP-heptose:LPS heptosyltransferase. | Histidinol-phosphate phosphatase family protein; COG0241 Histidinol phosphatase and related phosphatases. | 0.891 |