STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmD23S rRNA methyltransferase/RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (450 aa)    
Predicted Functional Partners:
EAR21482.1
Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
       0.799
EAR21480.1
Hypothetical protein; COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB.
       0.770
EAR22122.1
Hypothetical protein; COG0500 SAM-dependent methyltransferases.
   
  
 0.757
tmcA
Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
   
    0.712
EAR22383.1
Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.645
EAR20582.1
(p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     0.625
EAR21478.1
Signal transduction histidine kinase; COG0784 FOG: CheY-like receiver.
  
    0.584
EAR21479.1
Sensor histidine kinase/response regulator GacS; COG0642 Signal transduction histidine kinase.
  
    0.584
EAR21883.1
Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
      0.566
trmB
Predicted methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.555
Your Current Organism:
Nitrococcus mobilis
NCBI taxonomy Id: 314278
Other names: N. mobilis Nb-231, Nitrococcus mobilis Nb-231, Nitrococcus mobilis str. Nb-231, Nitrococcus mobilis strain Nb-231
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.