STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (363 aa)    
Predicted Functional Partners:
EAR20397.1
Hypothetical protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 0.999
EAR21370.1
Dihydroorotase family protein; COG0044 Dihydroorotase and related cyclic amidohydrolases.
 
 0.994
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.993
EAR22557.1
COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.
  
 0.988
EAR22174.1
Hypothetical protein; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.
  
 0.987
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
 
 
 0.985
carB
Carbamoyl-phosphate synthase, large subunit, glutamine-dependent; COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
 
 0.981
pyrB
COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.977
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.972
carA
COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family.
 
  
 0.965
Your Current Organism:
Nitrococcus mobilis
NCBI taxonomy Id: 314278
Other names: N. mobilis Nb-231, Nitrococcus mobilis Nb-231, Nitrococcus mobilis str. Nb-231, Nitrococcus mobilis strain Nb-231
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