STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR21009.1Atrazine chlorohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. (454 aa)    
Predicted Functional Partners:
hutI
COG1228 Imidazolonepropionase and related amidohydrolases.
 
 
 0.959
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
  
 0.888
hutH
COG2986 Histidine ammonia-lyase.
 
  
 0.673
EAR20593.1
5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
    
 0.487
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 
 0.483
EAR21796.1
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
    
 0.480
EAR20594.1
Phosphoribosyltransferase; COG0634 Hypoxanthine-guanine phosphoribosyltransferase.
    
 0.459
EAR21081.1
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
   
 0.457
EAR21074.1
Hypothetical protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation.
     
 0.456
EAR20397.1
Hypothetical protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 
  0.452
Your Current Organism:
Nitrococcus mobilis
NCBI taxonomy Id: 314278
Other names: N. mobilis Nb-231, Nitrococcus mobilis Nb-231, Nitrococcus mobilis str. Nb-231, Nitrococcus mobilis strain Nb-231
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