STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR22461.1COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. (212 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.986
rpoD
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.986
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.970
EAR22650.1
Adenylate/Guanylate Cyclase; COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain.
 
 
 0.968
rpoC
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.954
rpoZ
RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.953
EAR22518.1
COG0067 Glutamate synthase domain 1.
    
 0.924
EAR20358.1
Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Hpt; COG0642 Signal transduction histidine kinase.
  
 0.872
EAR20503.1
COG0642 Signal transduction histidine kinase.
  
 0.830
EAR21796.1
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
   
 0.778
Your Current Organism:
Nitrococcus mobilis
NCBI taxonomy Id: 314278
Other names: N. mobilis Nb-231, Nitrococcus mobilis Nb-231, Nitrococcus mobilis str. Nb-231, Nitrococcus mobilis strain Nb-231
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.